FMOC-(S)-3-AMINO-3-(2-THIENYL)-PROPANOIC ACID

FMOC-(S)-3-AMINO-3-(2-THIENYL)-PROPANOIC ACID - Names and Identifiers

Name	Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid
Synonyms	RARECHEM LK FC S196 FMOC-D-THG(2)-(CCH2)OH FMOC-D-BETA-ALA-(2-THIENYL)-OH FMOC-D-GLY(2-THIENYL)-(CCH2)OH Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid FMOC-(S)-3-AMINO-3-(2-THIENYL)-PROPIONIC ACID FMOC-(S)-3-AMINO-3-(2-THIENYL)-PROPANOIC ACID (S)-N-(9-FLUORENYLMETHOXYCARBONYL)-3-AMINO-3-(2-THIENYL)-PROPIONIC ACID (S)-3-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-THIOPHEN-2-YL-PROPIONIC ACID
CAS	507472-08-4

FMOC-(S)-3-AMINO-3-(2-THIENYL)-PROPANOIC ACID - Physico-chemical Properties

Molecular Formula	C22H19NO4S
Molar Mass	393.46
Density	1.341±0.06 g/cm3(Predicted)
Boling Point	627.8±55.0 °C(Predicted)
pKa	4.09±0.10(Predicted)
Storage Condition	2-8°C

FMOC-(S)-3-AMINO-3-(2-THIENYL)-PROPANOIC ACID - Introduction

Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid is an organic compound with a specific structure, which is obtained by combining Fmoc protecting group with S-3-amino -3-(2-thienyl) propionic acid. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White or light yellow solid
-Molecular formula: C24H20NO4S
-Molecular weight: 424.48g/mol
-Melting point: about 160-163°C
-Soluble: Soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane (DCM)

Use:
Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid is an amino acid derivative used in solid-phase synthesis. It is widely used in the synthesis of peptides, amino acids and other organic compounds, and as a protecting group in the synthesis of polypeptides.

Preparation Method:
The preparation of Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid is generally completed by the following steps:
1. At low temperature, Fmoc-gram acid (gram acylating agent) is reacted with S-3-amino -3-(2-thienyl) propionic acid.
2. The reaction is carried out in an alkaline environment to remove the Fmoc group in the protecting group.
3. Finally, the product is purified by crystallization or column chromatography.

Safety Information:
Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid is a chemical and should be operated in a laboratory environment. General laboratory practices and safety measures need to be observed during use. Avoid contact with skin and eyes, avoid breathing harmful gases or dust. Pay attention to personal protection when handling, such as wearing gloves, laboratory glasses and protective clothing. If splashed into eyes or skin, rinse immediately with plenty of water and seek medical help.

It should be noted that the above mentioned are only some basic information about Fmoc-S-3-Amino-3-(2-thienyl)-propionic acid, which should be studied and evaluated in more detail in combination with specific experiments or application requirements.

Last Update：2024-04-10 22:29:15